A major barrier to converting cancer therapies into cures is drug resistance. Cancer cells often develop resistance to even the most effective therapies. For instance, anti-VEGF therapies dramatically reduce tumor size initially, but some studies find that this response is only transient and tumors resume growth and progression after long-term treatment. Basic cell biology is critically needed to characterize these resistance pathways and uncover tools for monitoring the emergence of resistance pathways.
Image: A freeze-fracture SEM of a blood vessel that has grown into a melanoma and is providing nourishment to it. Numerous red blood cells can be seen within the blood vessel.
Two Part
Acrylic on wood. 9.5 by 13 inches. 2012.
Referenced with permission from this image by Flickr user Rosanna Jones.
EL SACRIFICIO (of the series El asesinato del conejo de Durero) | oil / canvas | 55.11 x 70.86 in | 2007
La Herida (The Wound), 2009
Oil on Canvas
untitled by Carolina Leal. on Flickr.